Clavis Pharma ASA Oslo, Norway, 30 June 2008

In accordance with the Employee Stock Option Plan dated 5 July 2006, the Board of Clavis Pharma ASA has on 30 June 2008 awarded in total 136,000 stock options to the following primary insiders:

+-------------------------------------------------------------------+ | Name | Position | Options | Options new | | | | granted | balance | |------------------+-----------------+--------------+---------------| | Geir Christian | Chief Executive | 40 000 | 100 000 | | Melen | Officer | | | |------------------+-----------------+--------------+---------------| | Ole Henrik | Chief Operating | 24 000 | 48 000 | | Eriksen | Officer | | | |------------------+-----------------+--------------+---------------| | Bo I. Nilsson | Chief Medical | 24 000 | 48 000 | | | Officer | | | |------------------+-----------------+--------------+---------------| | Gunnar Manum | Chief Financial | 24 000 | 48 000 | | | Officer | | | |------------------+-----------------+--------------+---------------| | Jan Alfheim | Chief Business | 24 000 | 46 000 | | | Officer | | | +-------------------------------------------------------------------+

In addition 87,000 stock options have been awarded to employees that are not defined as primary insiders. The stock options have a strike price of NOK 24,40, equal to the closing price of the shares at the date of awarding the stock options. The exercise period is from 1 July 2009 to 30 June 2010.

Contacts: Geir Christian Melen, CEO Office : +47 24 11 09 65 Mobile : +47 91 30 29 65 E-mail : geir.christian.melen@clavispharma.com

Gunnar Manum, CFO Office : +47 24 11 09 71 Mobile : +47 95 17 91 90 E-mail : gunnar.manum@clavispharma.com About Clavis Pharma Clavis Pharma ASA is an oncology focused pharmaceutical company using its proprietary Lipid Vector Technology (LVT) platform to create New Chemical Entities (NCEs), by significantly improving already established drugs. The improvements are achieved by chemically binding specific unsaturated lipids to existing, and well understood, approved pharmaceuticals. Data generated suggests the resulting patentable NCEs offer improved efficacy and reduced side effects through enhanced pharmacokinetic properties, greater tissue penetration and, in many cases, additional modes of action. Clavis Pharma's objective is to develop its drug candidates until significant value has been created and proof of principle in man has been shown. For further clinical development and commercialisation of the products, Clavis Pharma will enter into strategic partnerships with established pharmaceutical or biotech companies. The company's product portfolio includes three new cancer drugs, of which the first ELACYT(TM), is in Clinical Phase II, the second, CP-4126, is in Clinical Phase I, and the third, CP-4200, is in Preclinical Development. Results indicate that these products have promising potential for several cancer indications within solid tumours and leukaemia. The shares of Clavis Pharma ASA are listed on the Oslo Stock Exchange (ticker: CLAVIS). Additional information on Clavis Pharma can be found at: http://www.clavispharma.com/ .

About Leukaemia and AML Approximately 300,000 new cases of leukaemia are diagnosed globally each year, resulting in around 220,000 deaths. Leukaemia represents a market with high unmet medical needs, which may open for accelerated approval processes to expedite market access for new drugs. It is a segmented market covering a broad variety of disorders. A major clinical concern is the high rate of disease recurrence. The five-year survival for the most common acute leukaemia type, acute myeloid leukaemia (AML), is in the range of 5-10% for treated elderly patients, and approximately 30% for treated younger adults.

Disclaimer The information contained herein shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of the securities referred to herein in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration, exemption from registration or qualification under the securities laws of any such jurisdiction. This news release contains forward-looking statements and forecasts based on uncertainty, since they relate to events and depend on circumstances that will occur in the future and which, by their nature, will have an impact on results of operations and the financial condition of Clavis Pharma. There are a number of factors that could cause actual results and developments to differ materially from those expressed or implied by these forward-looking statements. Theses factors include, among other things, risks associated with technological development, the risk that research & development will not yield new products that achieve commercial success, the impact of competition, the ability to close viable and profitable business deals, the risk of non-approval of patents not yet granted and difficulties of obtaining relevant governmental approvals for new products. No expressed or implied representations or warranties are given concerning Clavis Pharma or the accuracy or completeness of the information or projections provided herein, and no claims shall be made by the recipient hereof by virtue of this Information Memorandum or the information or projections contained herein. Any representations or warranties made to an investor in Clavis Pharma will be subject to separate sale and purchase agreements to be negotiated between the parties. Clavis Pharma(TM) and ELACYT(TM) are registered trademarks of Clavis Pharma ASA.

Clavis Pharma ASA

http://www.clavispharma.com

ISIN: NO0010308240

Stock Identifier: XOSL.CLAVIS

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