Integral BioSystems spinoff Symphony Therapeutics will present drug development utilizing Integral's OcuHeal™ LNP platform
A substantial number of ophthalmic drug products for disorders of the ocular surface are hydrophobic, or sparingly soluble in water, and formulated as suspensions. This results in less than 5% of each eye-drop actually being absorbed by the target tissue. Such formulations typically contain a high concentration of drug to achieve a therapeutic effect. OcuHeal’s nanostructured emulsions are formulated into mucosa-penetrating, tissue absorbed nanoparticles, melting at body temperature to release dissolved drug at the requisite tissue site, allowing much less drug to be administered for equivalent or better therapeutic effect.
Symphony Therapeutics is developing an ophthalmic development pipeline utilizing this technology patented by Integral BioSystems, inviting the exploration of licensing-based collaborations for other potential applications in ophthalmic, dermal or other routes that can benefit from this technology.
Dave Karasic
Integral BioSystems, LLC
+1 617-820-8483
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