Wolters Kluwer NV (AMS:WLSN) Amsterdam (September 3, 2008) - Wolters Kluwer, a leading global information services and publishing company, announced that the company is in exclusive talks with the shareholders of UpToDate with respect to the acquisition of the U.S.-based UpToDate, a leading evidence-based electronic clinical information resource.

About Wolters Kluwer Wolters Kluwer is a leading global information services and publishing company. The company provides products and services globally for professionals in the health, tax, accounting, corporate, financial services, legal, and regulatory sectors. Wolters Kluwer has annual revenues (2007) of €3.4 billion, maintains operations in over 33 countries across Europe, North America, and Asia Pacific and employs approximately 19,500 people worldwide. Wolters Kluwer is headquartered in Amsterdam, the Netherlands. Its shares are quoted on the Euronext Amsterdam (WKL) and are included in the AEX and Euronext 100 indices. Visit www.wolterskluwer.com for information about our market positions, customers, brands, and organization.

Forward-looking Statements This press release contains forward-looking statements. These statements may be identified by words such as "expect," "should," "could," "shall," and similar expressions. Wolters Kluwer cautions that such forward-looking statements are qualified by certain risks and uncertainties that could cause actual results and events to differ materially from what is contemplated by the forward-looking statements. Factors which could cause actual results to differ from these forward-looking statements may include, without limitation, general economic conditions; conditions in the markets in which Wolters Kluwer is engaged; behavior of customers, suppliers, and competitors; technological developments; the implementation and execution of new ICT systems or outsourcing; and legal, tax, and regulatory rules affecting Wolters Kluwer's businesses, as well as risks related to mergers, acquisitions, and divestments. In addition, financial risks such as currency movements, interest rate fluctuations, liquidity, and credit risks could influence future results. The foregoing list of factors should not be construed as exhaustive. Wolters Kluwer disclaims any intention or obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise.



Contact: Caroline Wouters Kevin Entricken Vice President, Vice President, Corporate Communications Investor Relations Wolters Kluwer nv Wolters Kluwer nv + 31 (0)20 6070 459 + 31 (0)20 6070 407 press@wolterskluwer.com ir@wolterskluwer.com



LINK: http://hugin.info/130682/R/1248392/270656.pdf

Wolters Kluwer NV

http://www.wolterskluwer.com

ISIN: NL0000395903

Stock Identifier: XAMS.WLSN

US: PINKSHEETS:WTKWY

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