BB BIOTECH AG; Disclosure Of Shareholdings

Pursuant to article 20 BEHG BB BIOTECH AG, Vordergasse 3, 8200 Schaffhausen and its wholly-owned subsidiary Biotech Target N.V., Snipweg 26, Curaçao, Netherlands Antilles hereby report that they decreased their voting rights to below the threshold of 25% of the proportion of voting rights of BB BIOTECH AG as at August 21, 2008. 2'250'000 registered shares, which were bought during the 4th repurchase program terminated on April 3, 2008, and approved for cancellation at the AGM of April 4, 2008, were cancelled in the commercial register as at August 21, 2008. The share capital of BB BIOTECH AG now consists of 20'250'000 fully paid registered shares with a pair value of CHF 1.00 each.

Please find enclosed more details.



LINK: http://hugin.info/130285/R/1246325/269460.pdf

BB BIOTECH AG

ISIN: CH0038389992

Stock Identifier: XSWX.BION